Scientist, Upstream Process Development in Cambridge, MA at APEX Systems

Date Posted: 7/13/2019

Job Snapshot

Job Description

Job #:  931923
Scientist, Upstream Process Development, 931923
Job Scope & Purpose:
Our established Cambridge-based biotech partner is seeking a talented Scientist / Engineer to join a growing Upstream Process Development team. This critical team member will help develop the company’s novel cell culture bioprocessing platforms and advance therapeutics through clinical trials. The position will execute fed-batch and perfusion process development and design experiments to drive process scale-up, characterization and understanding at various scales, determine critical process parameters, develop process controls strategies for multiple stages (early stage development through clinical manufacturing phases), and generate harvest material to support research, non-clinical and downstream efforts. Additionally, this hire will work on tech transfers to CMOs. 
As part of a growing start-up company, you will be uniquely exposed to a broad range of activities both inside and outside of the laboratory. If you are ready to take on the challenge of working with a well-funded program and encouraging management, this is the Biotech for you. Contact the Stratacuity team today to learn more about these exclusive opportunities.
Primary Job Responsibilities:
  • Execution of fed-batch and perfusion process development and design of experiments to drive process understanding, process scale-up and characterization at various scales
  • Oversee harvesting of exosomes to support internal research activities as well as non-GLP and GLP nonclinical studies.
  • Lead technology transfer to CMOs and assist in the preparation of CMC documentation for regulatory and/or patent filings.
  • The ability to apply innovative, critical thinking and technical knowledge to analyze experimental results and communicate clearly to functional line management regarding progress against technical objectives/milestones is required.
  • Work in a team setting and interaction with other research and development groups will be expected.

Primary Job Requirements:
  • Ph.D. in Chemical Engineering, Biochemical Engineering, or an equivalent engineering/science degree with 2–4 years of industry experience.
  • Solid background with Mammalian cell culture, and perfusion experience is required.
  • Experience with ambr, bench-top and pilot scale bioreactor systems.
  • Strong background in process development and scale up/ down for Phase I–III clinical trial manufacturing.

About Stratacuity:
Whether you are seeking a career change or simply interested in becoming part of our network, you will appreciate the ethics guiding each Stratacuity team member. We build lasting relationships with exceptional biopharmaceutical talent and take great care to protect your personal information. Upon receiving your inquiry, you may be directly contacted by a Stratacuity team member to discuss your career goals. We will not share your information with anyone without your direct prior consent.
PROVEN SCIENTIFIC PLACEMENT™
Stratacuity is an Equal Employment Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Stratacuity will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact us at tjamison@stratacuity.com 877-787-2821.
Code:TechOps
 
 
 
 
 
 
 
 
EEO Employer
Apex is an Equal Employment Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact our Employee Services Department at 844-463-6178-6178.